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HOME
HPLC Topics
LC-MS TOPICS
HPLC Course
Educational
Links
Courses
Contact Me
Israel

HOME
HPLC Topics
LC-MS TOPICS
HPLC Course
Educational
Links
Courses
Contact Me
Israel

HOME
HPLC Topics
LC-MS TOPICS
HPLC Course
Educational
Links
Courses
Contact Me
Israel

LC-MS TOPICS

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GENERAL INFORMATION & RESOURCES אינפורמציה כללית ומשאבים
Articles, Posters & Reviews מאמרים, פוסטרים וסקירות
Atmospheric Pressure Ionization links יוניזציה בלחץ אטמוספרי
MS Technology Tutorials & Overviews מדריכים וסקירות על הטכנולוגיה
Proteomic Tutorials and lectures מדריכים בפרוטאומיקה
BIOINFORMATICS Tools כלים בביואינפורמטיקה
Utilities & Background Material חומר שימושי
Mass Spectroscopy – Sample Preparation הכנת דוגמאות
2D GEL ELECTROPHORESIS LINKS קישורים לאלקטרופורזת ג’ל
Metabonomics Tutorial and Tools
LC-MS Method Development פיתוח שיטות
Special Applications יישומים מיוחדים
Clinical LC-MS/MS – for Newborn disorders יישום רפואי

GENERAL INFORMATION & RESOURCES אינפורמציה כללית ומשאבים

Get the laboratory ready for liquid chromatography mass spectrometry work

Primer on LC-MS - Waters
Lecture on Bioanalytical and Clinical Tandem LC-MS/MS
Mass Spectrometry& Biotech Resources
LC-MS.com
History of Mass Spectrometry
Mass Spectrometry Portal
hyphen MassSpec Consultancy
Newobjective.com: Nano-Flow Accessories
Spektroscopy online - Wizard to identify your molecule
The Usenet Mass Spectrometry Newsgroup
Selecting water for HPLC
Magazine
MS Manufacturers
Sample Preparation and background material for proteins
PPT lecture at the School of Pharmacy, alberta, CA
Help Desk of Mass Spectrometry
Current Developments in LC-MS for Pharmaceutical Analysis

Articles, Posters & Reviews מאמרים, פוסטרים וסקירות

Troubleshooting LC-MS problems 5 mb (register first)
Principles of MS quantitation
Principles of Quadrupole and ion Trap
LC-MS primer

Atmospheric Pressure Ionization links יוניזציה בלחץ אטמוספרי

Charge state and mass assignment

Determining the Charge States of Multiply-Charged Ions

Example of mass spectra at various ionization modes

Electrospray ionization - lecture (pdf)

MS Technology Tutorials & Overviews מדריכים וסקירות על הטכנולוגיה

Reversed Phase: (Very good for beginners)
Handouts of my LC-MS Lecture at Forum Scientific (My courses' attendees: ask for the password)
Introduction to Mass Spectrometry at Scripps Center for Mass Spectrometry
Introduction to Mass Spectrometry
Introduction to Ion Trap Mass Spectrometer
Introduction to Quadrupole Time-of-Life
Basics of LC-ESI-MS-MS of Peptides
Theoretical Review of Mass Spectroscopic Techniques - Cambridge University
The Chemistry Hypermedia Project: MS Tutorial
GC-MS and MS Course with test

Proteomic Tutorials and lectures מדריכים בפרוטאומיקה

Peptide Sequencing with Electrospray LC/MS Part 1: Ion Types and Nomenclature by Frederick Klink
Labeled and Label Free Proteomics
Introduction to Bioinformatics - by Suresh Kumar
What is bioinformatics?
MASCOT Searches - Help Topic Index and background
Peptide fragmentation
Integration with the human genome of peptide sequences obtained by high-throughput mass
spectrometry
Introduction to Proteomics Part 1 by B. Tilg, A. Graber und K. Weinberger
Amino Acid Structures
Amino Acids chemistry

BIOINFORMATICS Tools כלים בביואינפורמטיקה

SUMMARY of links on searching Bio databases
MASCOT searches
Search for peptides and proteins in ExPASy
Swiss Prot general search
BLAST NCBI Search for peptides and protein ID HELP PAGE FOR BLAST
GlycoMod - Oligosaccharide structures from mass spectroscopy
GlycanMass - Oligosaccharide mass from structure
FindMod - Post-translational modifications by peptide mass
Pacific Nothwest National Laboratories USA: Proteomics Software Tools

Utilities & Background Material חומר שימושי

Help Desk of Mass Spectrometry
Download Spectra of Pesticides
Search for Delta Mass - A Database of Protein Post Translational Modifications
ChemCalc- calculate MW
Fragment Finder
AA to Peptide MW calculator
Periodic Table utility
Protein characterization and identification tools - Summary
Common Postranslational Modifications masses
Post translational modifications masses
More Delta masses of modifications
EMBL

Mass Spectroscopy - Sample Preparation הכנת דוגמאות

General Guidelines for Preparing Samples for MS Analysis - UTexes
Sample preparation references for MALDI
Sample preparation of Proteins for MS (PharmaGenomics November/December 2003)
Maintenance of HPLC system used for concentrated rough samples

2D GEL ELECTROPHORESIS LINKS קישורים לאלקטרופורזת ג'ל

2D GEL ELECTROPHORESIS FOR PROTEOMICS-TUTORIAL Arjan van Rossum A Basic Primer to Protein by Roger Biringer
Protocols on-line
2D Gel Electrophoresis - Proteomics from RSC
Amersham-Biosciences – SDS Gel Electrophoresis (visible only in IE)
SWISS-2DPAGE Two-dimensional polyacrylamide gel electrophoresis database

Metabonomics Tutorial and Tools

Chemometrics of metabonomics

LC-MS Method Development פיתוח שיטות

Eliminate TFA and Improve Sensitivity of Peptide Analyses by LC/MS
Narrow bore, micro and nano LC columns in LC-MS- J. MS
Determination of Carryover and Contamination for Mass Spectrometry – Based Chromatographic
Assays
Bioanalytical Method development of Therapeutic Peptides
FDA Guidance to the industry on validation of bioanalytical methods
Key Elements of Bioanalytical Method Validation for Small Molecules
Mass Spectrometry Adduct Calculator
"Ghost" peaks: Background contamination

Special Applications יישומים מיוחדים

Lipids and vitamin D Website

Clinical LC-MS/MS - for Newborn disorders יישום רפואי

Tandem Mass Spectrometry in Newborn Screening A Primer for Neonatal and Perinatal Nurses
Use of Tandem Mass Spectrometry Donald H. Chace,* Theodore A. Kalas, and Edwin W. Naylor
A Primer on Newborn Metabolic Screening
Expanded Newborn Screening for Inborn Errors of Metabolism by Electrospray Ionization
Screening for Inborn (MS/MS) Errors of Metabolism
The Expanding Role of Mass Spectrometry in Metabolite Profiling and Characterization
Elizabeth J. Want, Benjamin F. Cravatt, and Gary Siuzdak
Newborn screening - CDC
Utah Newborn Screening Training program
DIAGNOSIS OF INBORN ERRORS OF METABOLISM BY TANDEM MASS SPECTROMETRY Pinar T. Ozand
New York-guide for health professionals
ANALYSIS OF CARNITINE AND ACYLCARNITINES IN BIOLOGICAL FLUIDS AND APPLICATION TO A CLINICAL STUDY
Neonatal screening
Neonatal screening for inborn errors of metabolism
New developments in neonatal screening

Reagents for Acylcarnitines and Amino acids analysis in blood spots ריאגנטים עבור אנליזה לתינוקות
Bulanolic HCl - Regis Technologies
Cambridge Isotopes Laboratory
Materials and Methods for acylcarnitine analysis by MS/MS
Metabolic Laboratory: Standards for metabolic research
Experimental: Article-Clin Chem 51:4 745–752 (2005)
Protocol (ppt)

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